Physicians warned of possible adverse events from rituximab, (May 16, 2001) [eCMAJ]

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Physicians warned of possible adverse events from rituximab (Rituxan) (May 16, 2001)

Hoffman-La Roche Ltd. has issued a that rituximab (Rituxan), used in the treatment of some patients with B-cell lymphoma, may cause severe mucocutaneous reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, paraneoplastic pemphigus, lichenoid dermatitis or vesiculobullous dermatitis). To date there have been 20 such reports worldwide, including 8 deaths.