MET gene and breast cancer

Table 1: Characteristics of 80 patients with breast cancer studied
CharacteristicNo. (and %) of patients
Loss of heterozygosity (LOH)
  • Noninformative
  • Informative
    LOH-negative
    LOH-positive
    Unknown
    		•  32 (40)
     
    28 (35)
    8 (10)
    12 (15)
    Age
  • < 50 yr
  • >= 50 yr
    		•  21 (26)
    59 (74)
    Size of tumour
  • <= 2 cm
  • > 2 cm, <= 5 cm
  • > 5 cm
    		•  15 (19)
    51 (64)
    14 (17)
    Histologic type of tumour
  • Infiltrating ductal
  • Infiltrating lobular
  • Infiltrating mixed
    		•  70 (88)
    5 (6)
    5 (6)
    Histologic grade
  • I
  • II
  • III
  • Unknown
    		•  9 (11)
    34 (42)
    35 (44)
    2 (3)
    No. of lymph nodes with metastasis
  • 0
  • 1-3
  • >= 4
  • Unknown
    		•  7 (9)
    25 (31)
    20 (25)
    28 (35)
    Estrogen-receptor (ER) status
  • Negative
  • Positive
  • Unknown
    		•  41 (51)
    35 (44)
    4 (5)
    Progesterone-receptor (PR) status
  • Negative
  • Positive
  • Unknown
    		•  41 (51)
    35 (44)
    4 (5)
    c-erbB-2 staining
  • Negative
  • Positive
  • Unknown
    		•  62 (78)
    16 (20)
    2 (2)
    Ploidy
  • Diploid
  • Aneuploid
  • Unknown
    		•  16 (20)
    33 (41)
    31 (39)
    S-phase fraction
  • < 6%
  • >= 6%
  • Unknown
    		•  17 (21)
    23 (29)
    40 (50)