MET gene and breast cancer

Table 2: Characteristics of the 36 informative patients

No. (and %) of patients

Characteristic Without LOH With LOH

Age
< 50 yr
>= 50 yr
10 (83)
18 (75) 2 (17)
6 (25)

Size of tumour
<= 2 cm
> 2 cm, <= 5 cm
> 5 cm
6 (100)
18 (75)
4 (67) 0
6 (25)
2 (33)

Histologic type of tumour
Infiltrating ductal
Infiltrating lobular
Infiltrating mixed
25 (78)
1 (50)
2 (100) 7 (22)
1 (50)
0

Histologic grade
I
II
III
3 (75)
15 (83)
10 (71) 1 (25)
3 (17)
4 (29)

Lymph nodes
Without metastasis
With metastasis
5 (71)
23 (79) 2 (29)
6 (21)

ER status
Negative
Positive
15 (75)
13 (81) 5 (25)
3 (19)

PR status
Negative
Positive
13 (68)
15 (88) 6 (32)
2 (12)

c-erbB-2 staining
Negative
Positive
22 (73)
6 (100) 8 (27)
0

Ploidy
Diploid
Aneuploid
Unknown
7 (100)
9 (69)
12 (75) 0
4 (31)
4 (25)

S-phase fraction
< 6%
>= 6%
Unknown
6 (86)
6 (75)
16 (76) 1 (14)
2 (25)
5 (24)

Table 2: Characteristics of the 36 informative patients
	No. (and %) of patients
Characteristic	Without LOH	With LOH
Age < 50 yr >= 50 yr	10 (83) 18 (75)	2 (17) 6 (25)
Size of tumour <= 2 cm > 2 cm, <= 5 cm > 5 cm	6 (100) 18 (75) 4 (67)	0 6 (25) 2 (33)
Histologic type of tumour Infiltrating ductal Infiltrating lobular Infiltrating mixed	25 (78) 1 (50) 2 (100)	7 (22) 1 (50) 0
Histologic grade I II III	3 (75) 15 (83) 10 (71)	1 (25) 3 (17) 4 (29)
Lymph nodes Without metastasis With metastasis	5 (71) 23 (79)	2 (29) 6 (21)
ER status Negative Positive	15 (75) 13 (81)	5 (25) 3 (19)
PR status Negative Positive	13 (68) 15 (88)	6 (32) 2 (12)
*c-erbB-2 staining* Negative Positive	22 (73) 6 (100)	8 (27) 0
Ploidy Diploid Aneuploid Unknown	7 (100) 9 (69) 12 (75)	0 4 (31) 4 (25)
S-phase fraction < 6% >= 6% Unknown	6 (86) 6 (75) 16 (76)	1 (14) 2 (25) 5 (24)