The genetic basis of primary disorders of intestinal fat transport


Table 2: Characteristics of intestinal apolipoproteins
ApolipoproteinMolecular mass, kdPropeptide*Mature protein**Gene length, kbmRNA length, kbFunction
A-I 28182431.90.893Lecithin cholesterol acyltransferase activator
Reverse cholesterol transport
A-IV46203762.61 469Reverse cholesterol transport
Satiety
Gastric acid secretion
B-48275272 15267-8Structural role
Lipoprotein assembly and secretion
B-100550None4 5364414 121Structural role
Lipoprotein assembly and secretion
Low-density lipoprotein receptor ligand
*Amino acids of plasma apolipoproteins.
**Apo B-100 and apo B-48 are derived from the same gene. B-48 arises from a novel form of RNA editing.

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