Table 2: Characteristics of intestinal apolipoproteins | ||||||
Apolipoprotein | Molecular mass, kd | Propeptide* | Mature protein** | Gene length, kb | mRNA length, kb | Function |
A-I | 28 | 18 | 243 | 1.9 | 0.893 | Lecithin cholesterol acyltransferase activator Reverse cholesterol transport |
A-IV | 46 | 20 | 376 | 2.6 | 1 469 | Reverse cholesterol transport Satiety Gastric acid secretion |
B-48 | 275 | 27 | 2 152 | 6 | 7-8 | Structural role Lipoprotein assembly and secretion |
B-100 | 550 | None | 4 536 | 44 | 14 121 | Structural role Lipoprotein assembly and secretion Low-density lipoprotein receptor ligand |
*Amino acids of plasma apolipoproteins. **Apo B-100 and apo B-48 are derived from the same gene. B-48 arises from a novel form of RNA editing. |