Table 2: Summary of tests of various liver-assist devices conducted in animals | ||||
Study | Animal | Cause of liver disease | Support time, h | Result |
Rozga et al25 | Dog | Ischemia | 6 | Biochemical improvement Cardiovascular stability |
Jauregui et al29 | Rabbit | Galactosamine | 6 | Delayed onset of encephalopathy Better survival rate after 80 h (in 4/11 v. 2/22) |
Li* | Pig | Anhepatic | 3-12 | Survival |
Sussman et al21,31 | Dog | Acetaminophen | 48 | Survival |
*Dr. Albert P. Li, In Vitro Technologies, Baltimore, Md: personal communication, 1994. |