Table 4: Results of ANF administration after isoncotic dextran solution infusion in four dogs | ||||
Mean (and standard error of the mean) | ||||
Result | Before ANF or alloxan administration | After administration of alloxan and dextran | After administration of ANF | During recovery |
Urinary flow, mL/min | 0.29 (0.03) | 1.77* (0.16) | 3.75* (0.44) | 2.9* (0.28) |
Urinary sodium excretion, µmol/min | 62 (12) | 245* (19) | 462* (23) | 179* (16) |
Glomerular filtration rate, mL/min | 38 (3) | 22* (3.4) | 23 (3.3) | 19 (2.7) |
Para-amino hippurate clearance, mL/min | 135 (14) | 148 (12) | 119* (11) | 95* (9.3) |
Plasma protein concentration, g/L | 48 (0.8) | 42* (0.7) | 43 (0.9) | 43 (0.9) |
Hematocrit | 0.42 (0.017) | 0.36* (0.014) | 0.37 (0.014) | 0.425* (0.013) |
Central venous pressure, cm H20 | 7 (0.08) | 7 (0.7) | 7 (0.7) | 6* (0.9) |
Arterial blood pressure, mm Hg | 100 (8.6) | 100 (9.3) | 80* (7.0) | 100* (12.0) |
*p < 0.05 compared with the previous experimental phase. |