Table 5: Results of alloxan administration after an infusion of catalase in eight dogs | |||
Mean (and standard error of the mean) | |||
Result | Before administration of alloxan or catalase | After administration of catalase and alloxan | After administration of ANF |
Urinary flow, mL/min | 0.6 (0.09) | 0.84* (0.11) | 3.5* (0.22) |
Urinary sodium excretion, µmol/min | 132 (18) | 145 (24) | 254* (27) |
Glomerular filtration rate, mL/min | 20 (1.9) | 18 (1.7) | 21* (2.0) |
Para-amino hippurate clearance, mL/min | 76 (8.5) | 71 (9.1) | 66 (10) |
Plasma protein concentration, g/L | 48 (0.7) | 48 (0.8) | 46 (0.9) |
Hematocrit | 0.473 (0.013) | 0.474 (0.014) | 0.430* (0.016) |
Central venous pressure, cm H20 | 6 (1) | 6 (0.9) | 5.8 (0.9) |
Arterial blood pressure, mm Hg | 110 (7.0) | 107 (7.8) | 100* (8.3) |
*p < 0.05 compared to the previous experimental phase. |