Renal natriuretic effects of atrial natriuretic peptide in dogs with alloxan-induced acute pulmonary edema

Table 5: Results of alloxan administration after an infusion of catalase in eight dogs
 Mean (and standard error of the mean)
Result Before administration of alloxan or catalase After administration of catalase and alloxan After administration of ANF
Urinary flow, mL/min 0.6 (0.09) 0.84* (0.11) 3.5* (0.22)
Urinary sodium excretion, µmol/min 132 (18) 145 (24) 254* (27)
Glomerular filtration rate, mL/min 20 (1.9) 18 (1.7) 21* (2.0)
Para-amino hippurate clearance, mL/min 76 (8.5) 71 (9.1) 66 (10)
Plasma protein concentration, g/L 48 (0.7) 48 (0.8) 46 (0.9)
Hematocrit 0.473 (0.013) 0.474 (0.014) 0.430* (0.016)
Central venous pressure, cm H20 6 (1) 6 (0.9) 5.8 (0.9)
Arterial blood pressure, mm Hg 110 (7.0) 107 (7.8) 100* (8.3)
*p < 0.05 compared to the previous experimental phase.

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