Effects of substituting dietary soybean protein and oil for milk protein and fat in subjects with hypercholesterolemia

Table 3: Effects of diets on plasma lipoprotein profile
 Mean ( and standard deviation)
  Dietary period
Clinical level BaselineMilk Milk/soy oil Soybean
Plasma lipid level, mmol/L
Total cholesterol 6.86 (0.99)6.90 (1.00) 6.96 (1.15) 6.98 (1.23)
VLDL cholesterol 0.85 (0.43)0.86 (0.39) 0.93 (0.42) 0.89 (0.48)
LDL cholesterol 4.45 (0.95)4.36 (1.07) 4.29 (1.15) 4.26 (1.04)
HDL cholesterol 1.31 (0.32)1.30* (0.41) 1.37 (0.38) 1.40* (0.28)
% change in HDL cholesterol   -1 49
LDL/HDL ratio 3.61 (1.25)3.63H (1.33) 3.38 (1.38) 3.12† (1.05)
% change in ratio  0 -7 -14
Total triglyceride level, mmol/L 1.75 (0.64)1.85 (0.72) 1.90 (0.85) 1.94 (0.83)
Apolipoprotein B, g/L 148 (35)148 (32) 148 (36) 148 (34)
Apolipoprotein A1, g/L 144 (28)138 (26) 141 (29) 135 (27)
Systolic blood pressure, mm Hg 131 (17)123* (15) 124 (15) 128* (15)
Diastolic blood pressure, mm Hg 77 (10)73‡ (10) 77 (9)77‡ (8)
Plasma peroxide level, mol/L 1.35 (0.43) 1.26§ (0.43) 1.36 (0.43) 1.41§ (0.55)
*The 2 values marked in this row are significantly different (p = 0.04) based on pairwise comparison of change from baseline.
†The 2 values marked in this row are significantly different (p = 0.007) based on pairwise comparison of change from baseline.
‡The 2 values marked in this row are significantly different (p = 0.02) based on pairwise comparison of change from baseline.
§The 2 values marked in this row are significantly different (p = 0.01) based on pairwise comparison of change from baseline.

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| CIM: June 1997 (vol 20, no 3) / MCE : juin 1997 (vol 20, no 3) |

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