Fig. 1: Platelet proteins were separated on nonreduced denaturing gels containing acrylamide (left panel: 1%; right panel: 1.5%) and 1.25% agarose. Left panel: An immunoblot analysis comparing multimerin and von Willebrand factor. These proteins are composed of different-sized multimers; they differ in their nonreduced mobility. Right panel: A comparison of the multimerin found in platelet lysate and releasate. Only small multimerin oligomers are secreted into releasate when platelets are activated by strong agonists such as thrombin.[5] Reproduced with permission.
[ Return to text ]