High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F

Fig. 5: IIF staining of a breast tumour sample reacted with DAPI (a and d), Ki-67 (b and e) and CENP-F (c and f). A G2 pattern of CENP-F reactivity was found in only 1 of 3 Ki-67 reactive cells, shown in panels a to c (arrows). Panels d and e illustrate a mitotic cell displaying the typical halo pattern of staining produced by Ki-67 antibodies. Panel f shows a punctate centromere pattern typical of CENP-F antibodies. Original magnification × 3000.

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| CIM: October 1997 (vol 20, no 5) / MCE : octobre 1997 (vol 20, no 5) |

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