High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F

Table 2: Summary of reactivity of CENP­F patient sera with CENP­F (pF) epitopes
  Epitope; no. (and %) of patients
Patient group pF1 pF2 pF3 pF4 pF5
Total patients 16/30 (53) 24/33 (73) 23/33 (70) 26/33 (79) 24/31 (77)
Patients with neoplasm 9/19 (47) 18/21 (86) 17/21 (81) 21/21 (100) 19/20 (95)
Patients without neoplasm 7/11 (63) 6/12 (50) 6/12 (50) 5/12 (42) 5/11 (45)
Statistic
p value* 0.4664 0.0441 0.1142 0.0002 0.0036
Odds ratio 0.5143 6.000 4.250 58.636 22.800
95% confidence interval† 0.1121-2.360 1.134-31.748 0.8833-20.449 2.882-1192.9 2.206-235.65
*Fisher's exact test.
†Using the approximation of Woolf.

[ Return to text ]


| CIM: October 1997 (vol 20, no 5) / MCE : octobre 1997 (vol 20, no 5) |

CMA Webspinners / >