Fig. 6: (A) Light micrograph of a cerebral cortex section from a SHRSP in the 8-week treatment/withdrawal group, showing a large blood vessel (small arrow) subjacent to glia limitans. The vessel has markedly thickened hyaline-like wall and is adjacent to a large area of massive fibrin deposition and necrosis (large arrow). The surrounding area contains diffuse intense gliosis and markedly accentuated capillary blood vessels (microvascular proliferation). The bar represents 50 µm. (B) Cerebral cortex section from the same animal as Fig. 6A, in an area with malacia. Two small blood vessels with markedly thickened wall are surrounded by numerous scattered macrophages with abundant hemosiderin and by gliosis. The bar represents 20 µm.
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