Limiting the Niemann­Pick Type C critical region to a 1-cM interval

Fig. 1: Segregation pattern in a NPC family of 12 polymorphic microsatellite loci from pericentromeric chromosome 18. Allele sizes (in base pairs) are indicated for each haplotype. Bracketed alleles were deduced. Phase has not been established for individual I-2. The recombination between microsatellite markers D18S1397 and D18S1101 has been arbitrarily represented for individual II-2.

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| CIM: October 1997 (vol 20, no 5) / MCE : octobre 1997 (vol 20, no 5) |

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