Limiting the Niemann­Pick Type C critical region to a 1-cM interval

Fig. 2: Cholesterol esterification in cultured lymphoblasts obtained from members of the NPC family (father [I-1], mother [I-2], proband [II-1] and unaffected daughter [II-2]) and from an unrelated individual (control). Solid bars represent cholesterol esterification (nmol/h/mg protein) in response to 6-hour incubation with fetal bovine serum (FBS) (mean and standard deviation, n = 3), and white bars represent controls without FBS (single sample).

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| CIM: October 1997 (vol 20, no 5) / MCE : octobre 1997 (vol 20, no 5) |

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