Fig. 1: Can you tell the difference? From left to right, Benadryl allergy formula contains diphenhydramine, whereas Benadryl decongestant/allergy contains diphenhydramine plus pseudoephedrine; Chlor-Tripolon regular contains chlorpheniramine, whereas Chlor-Tripolon N.D. (non-drowsy) contains loratadine and pseudoephedrine; Claritin skin itch contains loratadine, whereas Claritin Extra allergy and sinus contains loratadine plus pseudoephedrine.