Pharmacologic treatment of hypertensive disorders in pregnancy

 

Table 3: Recommended treatment of severe hypertension in pregnancy
Treatment goal
DPB 90-100 mm Hg (grade D)
First-line drugs
Hydralazine (grade B)66-68
Labetalol (grade B)66,69,70
Nifedipine (grade B)67,71,72
Special indications (patient refractory to first-line drugs)
Diazoxide (grade D)
Sodium nitroprusside (grade D)
Caution
  • Neuromuscular function and blood pressure should be closely monitored when using nifedipine + magnesium sulfate (grade D)
  • Fetal heart rate should be monitored during acute treatment (grade D)

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| CMAJ November 1, 1997 (vol 157, no 9) / JAMC le 1er novembre 1997 (vol 157, no 9) |

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