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Tuberculosis: 5. Pediatric disease
| Table 4: Pediatric dosages of commonly used antituberculous drugs |
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Frequency of administration; recommended dose, mg/kg (and maximum dose) |
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| Drug |
Daily |
Twice per week |
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| Isoniazid* |
10–20 |
(30 mg/d) |
20–40 |
(900 mg/dose) |
| Rifampin* |
10–20 |
(600 mg/d) |
10–20 |
(600 mg/dose) |
| Pyrazinamide |
20–40 |
(2 g/d) |
50–70 |
(4 g/dose) |
| Ethambutol |
15–25 |
(2.5 g/d) |
50 |
(2.5 g/dose) |
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| *If isoniazid plus rifampin are to be given together on a daily basis, the doses should be 10 mg isoniazid per kilogram and 15 mg rifampin per kilogram. |
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