Factors affecting glucose tolerance in hereditary hemochromatosis

Table 2: Metabolic parameters of subjects
Metabolic parameterMean (and SEM)
Normal controls
n = 10
Subjects with HH
n = 7
Subjects with HH and cirrhosis
n = 4
Subjects with HH
and diabetes mellitus
n = 6
Fasting plasma glucose level, mmol/L 4.9 (0.1) 5.0 (0.2)5.5 (0.3)8.1 (0.4)*
Fasting plasma insulin level, pmol/L 108.5 (13.7) 85.8 (17.9)153.9 (39.3)97.1 (20.4)
Basal C-peptide, nmol/L 0.61 (0.10)0.58 (0.07) 0.80 (0.08)0.46 (0.13)
C-peptide to insulin ratio 5.9 (0.5)7.8 (1.4) 6.1 (1.2)5.8 (1.9)
Kg, % × min-12.4 (0.4)1.4 (0.2)* 1.4 (0.2)*1.2 (0.02)*
SG × 10-2, min-1 1.9 (0.2) 1.6 (0.3) 1.6 (0.1) 2.0 (0.4)
*Significantly different from normal subjects (p < 0.05).

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| CIM: April 1997 (vol 20, no 2) / MCE : avril 1997 (vol 20, no 2) |
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