Clin Invest Med: April 1997 / Table 3: Factors affecting glucose tolerance in hereditary hemochromatosis

Factors affecting glucose tolerance in hereditary hemochromatosis

Table 3: Metabolic parameters of subjects before and after treatment with phlebotomy
Metabolic parameter	Mean (and SEM)
	Normal controls n = 10	Subjects with HH n = 6		Subjects with HH and cirrhosis n = 4		Subjects with HH and diabetes mellitus n = 4
	Normal controls n = 10	Before treatment	After treatment	Before treatment	After treatment	Before treatment	After treatment
Ferritin level, µg/L	100 (25)	937 (165)*	86 (50)†	3220 (199)*	107 (67)†	1356 (403)*	59 (21)†
Insulin sensitivity, min^-1 per nmol/mL	42.6 (7.8)	48.3 (8.7)	35.8 (8.3)	14.3 (4.4)*	13.7 (3.0)*	21.0 (10.8)*	15.8 (7.3)*
AIR_g, pmol/L min	408 (77.0)	301 (57.1)	407 (53.7)	409 (49.8)	427 (97.0)	41.0 (5.2)*	37.8 (17.8)*
K_g, % × min^-1	2.4 (0.4)	1.4 (0.2)*	2.2 (0.2)	1.4 (0.2)*	1.5 (0.2)*	1.2 (0.2)*	0.7 (0.2)*
*Significantly different from normal subjects (p< 0.05). †Prephlebotomy and postphlebotomy values are significantly different (p< 0.05).