CMAJ/JAMC News and analysis
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Hundreds enrolled in Canadian HIV trials

CMAJ 1997;156:1691
Canadian volunteers are being enrolled in a protease inhibitor study that is the first large-scale collaborative clinical trial involving the Canadian HIV Trials Network (CTN) and American researchers. According to CTN's Network Update, the study hopes to enrol 400 volunteers in Canada within a year. Participants will be randomized to receive either ritonavir or the newer drug, nelfinavir.

Network Update also gave a clear picture of the breadth of HIV trials in Canada, identifying 22 studies that are currently enrolling participants in several cities. CTN clinical trials include studies comparing the usefulness of 2-drug combinations following treatment with AZT and studies seeking the highest dose of etoposide and doxorubicin that can be tolerated when part of VACOP-B combination chemotherapy; for information visit www.hivnet.ubc.ca/ctn.html, or call 800 661-4664. Non-CTN trial information is provided by the Community AIDS Treatment Information Exchange; visit www.catie.ca or call 800 263-1638.

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| CMAJ June 15, 1997 (vol 156, no 12) / JAMC le 15 juin 1997 (vol 156, no 12) |