First-line treatment of seasonal (ragweed) rhinoconjunctivitis

 

Table 1: Characteristics of patients with seasonal (ragweed) rhinoconjunctivitis entered into study comparing fluticasone nasal spray with terfenadine tablets as first-line treatment
CharacteristicTreatment group; no. of patients*
Fluticasone n = 31 Terfenadine n = 30
Sex (male/female)15/16 16/14
Mean age (and SD†), yr41.0 (11.4) 45.7 (10.5)
Mean diameter (and SD) of wheals after duplicate skin­prick test with 5 concentrations of ragweed pollen extract 3.77 (1.23)3.77 (1.26)
Severity of hay fever symptoms the previous year
   Mild
   Moderate
   Severe
14
12
5
11
12
7
Medications taken for hay fever the previous year
   Antihistamine alone
   Nasal steroid alone
   Antihistamine + nasal steroid
16
6
9
10
11
9
Skin sensitivity to fungal spores 1315
Skin sensitivity to grass pollen 2523
No previous experience in clinical studies 87
Nasal steroid used within 6 weeks before randomization 02
*Unless otherwise stated.
†SD = standard deviation.

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| CMAJ April 15, 1997 (vol 156, no 8) / JAMC le 15 avril 1997 (vol 156, no 8) |
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