Table 1: Characteristics of patients with seasonal (ragweed) rhinoconjunctivitis entered into study comparing fluticasone nasal spray with terfenadine tablets as first-line treatment | ||
Characteristic | Treatment group; no. of patients* | |
Fluticasone n = 31 | Terfenadine n = 30 | |
Sex (male/female) | 15/16 | 16/14 |
Mean age (and SD), yr | 41.0 (11.4) | 45.7 (10.5) |
Mean diameter (and SD) of wheals after duplicate skinprick test with 5 concentrations of ragweed pollen extract | 3.77 (1.23) | 3.77 (1.26) |
Severity of hay fever symptoms the previous year
Mild Moderate Severe |
14 12 5 |
11 12 7 |
Medications taken for hay fever the previous year
Antihistamine alone Nasal steroid alone Antihistamine + nasal steroid |
16 6 9 |
10 11 9 |
Skin sensitivity to fungal spores | 13 | 15 |
Skin sensitivity to grass pollen | 25 | 23 |
No previous experience in clinical studies | 8 | 7 |
Nasal steroid used within 6 weeks before randomization | 0 | 2 |
*Unless otherwise stated.
SD = standard deviation. |