CMAJ - April 15, 1997 / Table 2: First-line treatment of seasonal (ragweed) rhinoconjunctivitis

First-line treatment of seasonal (ragweed) rhinoconjunctivitis

Table 2: Differences in mean scores for health-related quality of life (HRQL)* between the treatment groups (after adjustment for differences at baseline)

Domain Difference in mean scores† p value§

Height of season‡ End of season‡ Treatment effect Time effect

Sleep impairment
Non-nasal symptoms
Practical problems
Nasal symptoms
Eye symptoms
Activity limitations
Emotional function
-0.03
0.17
0.15
0.21
-0.27
0.20
0.23
0.15
0.09
0.39
0.31
0.04
0.33
0.05
0.054
0.274
0.015
0.005
0.614
0.037
0.165
0.0037
0.0052
0.0001
0.0035
0.0001
0.0002
0.0003

Overall 0.11 0.14 0.052 0.0001

*HRQL determined using Rhinoconjunctivitis Quality of Life Questionnaire³ scores (0 = not bothered, 6 = extremely bothered).
†Minimal important difference = 0.5.
‡Positive differences indicate better HRQL for patients in the fluticasone group.
§Repeated measures analysis with covariate adjustment for differences in baseline score.

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| CMAJ April 15, 1997 (vol 156, no 8) / JAMC le 15 avril 1997 (vol 156, no 8) |

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*Table 2: Differences in mean scores for health-related quality of life (HRQL) between the treatment groups (after adjustment for differences at baseline)**
Domain	Difference in mean scores†		p value§
Domain	Height of season‡	End of season‡	Treatment effect	Time effect
Sleep impairment Non-nasal symptoms Practical problems Nasal symptoms Eye symptoms Activity limitations Emotional function	-0.03 0.17 0.15 0.21 -0.27 0.20 0.23	0.15 0.09 0.39 0.31 0.04 0.33 0.05	0.054 0.274 0.015 0.005 0.614 0.037 0.165	0.0037 0.0052 0.0001 0.0035 0.0001 0.0002 0.0003
Overall	0.11	0.14	0.052	0.0001
*HRQL determined using Rhinoconjunctivitis Quality of Life Questionnaire³ scores (0 = not bothered, 6 = extremely bothered). †Minimal important difference = 0.5. ‡Positive differences indicate better HRQL for patients in the fluticasone group. §Repeated measures analysis with covariate adjustment for differences in baseline score.