Table 6: Hemostatic markers in control subjects | ||||
Marker | Control group; mean value (and SD) | Difference in means (and 95% CI) | Adjusted p value* | |
With history of stroke n = 11 | Without history of stroke n = 31 | |||
Fibrinogen, g/L | 4.0 (0.9) | 3.2 (1.1) | 0.8 (0.16, 1.43) | 0.04 |
Von Willebrand factor antigen, µ/mL | 2.3 (1.2) | 1.5 (0.6) | 0.8 (0.06, 1.53) | 0.002 |
Factor VIII, µ/mL | 1.7 (0.7) | 1.3 (0.3) | 0.4 ( 0.05, 0.85) | 0.002 |
Protein C, µ/mL | 0.91 (0.23) | 1.10 (0.24) | 0.19 ( 0.35, 0.03) | 0.08 |
Protein S, µ/mL | 0.86 (0.09) | 0.98 (0.17) | 0.12 ( 0.20, 0.04) | 0.023 |
Prothrombin fragment F1+2, nmol/L | ||||
All subjects | 1.5 (1.43) | 1.8 (0.99) | 0.30 ( 1.20, 0.60) | 0.46 |
Excluding outliers | 1.04 (0.27) | 1.72 (0.97) | 0.68 ( 1.10, 0.30) | 0.06 |
n = 7 | n = 29 | |||
*Determined by ANOVA, for difference between groups after adjustment for age and sex.
As described in Table 4. |