Table 2: Increased tissue plasminogen activator levels in patients with nonvalvular atrial fibrillation / CMAJ

Increased tissue plasminogen activator levels in patients with nonvalvular atrial fibrillation

Table 2: Mean endogenous tissue plasminogen activator (tPA) levels and range

Patient group tPA level, ng/mL

Mean (and SD) Range*

NVAF patients

   Group 1 13.1  (4.9)† 3.8-23.0

   Group 2 15.6  (6.1)† 7.4-35.0

   Group 3 13.5  (4.8)† 5.6-25.6

Control subjects

   No prior thrombotic stroke 10.6  (3.5) 3.7-18.4

   Prior thrombotic stroke 14.5  (8.2)‡ 4.2-30.1

*Laboratory reference range 0.1-11.7 ng/mL.
†p = 0.015, compared with control subjects with no prior thrombotic stroke, by analysis of variance (ANOVA) after adjustment for age.
‡p = 0.03, compared with control subjects with no prior thrombotic stroke, by ANOVA after adjustment for age.

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| CMAJ September 15, 1997 (vol 157, no 6) / JAMC le 15 septembre 1997 (vol 157, no 6) |

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Table 2: Mean endogenous tissue plasminogen activator (tPA) levels and range
Patient group	tPA level, ng/mL
Patient group	Mean (and SD)	Range*
NVAF patients
Group 1	13.1 (4.9)†	3.8-23.0
Group 2	15.6 (6.1)†	7.4-35.0
Group 3	13.5 (4.8)†	5.6-25.6
Control subjects
No prior thrombotic stroke	10.6 (3.5)	3.7-18.4
Prior thrombotic stroke	14.5 (8.2)‡	4.2-30.1
*Laboratory reference range 0.1-11.7 ng/mL. †p = 0.015, compared with control subjects with no prior thrombotic stroke, by analysis of variance (ANOVA) after adjustment for age. ‡p = 0.03, compared with control subjects with no prior thrombotic stroke, by ANOVA after adjustment for age.