Table 3: Proposed classification of hypertensive disorders in pregnancy | |
Classification | Definition |
A. Pre-existing hypertension | Diastolic hypertension (as defined in Table 1) that predates pregnancy or is diagnosed before 20 weeks' gestation. In most cases hypertension persists > 42 d post partum. It may be associated with proteinuria. |
1. Essential | Primary |
2. Secondary | Secondary to such conditions as renal disease, pheochromocytoma and Cushing syndrome |
B. Gestational hypertension | Diastolic hypertension develops after 20 weeks' gestation. In most cases it resolves < 42 d postpartum |
1. Without proteinuria | Corresponds to previous terminology such as "pregnancy-induced hypertension," "transient hypertension" and "nonproteinuric hypertension." Protein excretion in 24hour urine collection is < 0.3 g/d |
a. Without adverse conditions | |
b. With adverse conditions | Convulsions (eclampsia); very high diastolic pressure (> 110 mm Hg); thrombocytopenia (platelet count < 100 000 X 109/L); oliguria (< 500 mL/d); pulmonary edema; elevated liver enzyme levels; severe nausea and vomiting, frontal headache, visual disturbances, persistent abdominal pain in right upper quadrant, chest pain or shortness of breath; suspected abruptio placentae; HELLP syndrome; intrauterine growth retardation, oligohydramnios, or absent or reversed umbilical artery end diastolic flow, as determined by Doppler velicitometry |
2. With proteinuria | Corresponds to previous terminology such as "preeclampsia," "pre-eclamptic toxemia" and "toxemia." Protein excretion in 24-hour urine collection is 0.3 g/d |
a. Without adverse conditions | |
b. With adverse conditions | Same conditions as in 1b; protein excretion > 3 g/d in 24-h urine collection, especially with hypoalbuminemia (albumin level < 18 g/L) |
C. Pre-existing hypertension + superimposed gestational hypertension with proteinuria | Pre-existing hypertension (as defined in A) associated with further worsening of blood pressure and protein excretion 3 g/d in 24-h urine collection after 20 weeks' gestation. Corresponds to previous terminology "chronic hypertension with superimposed pre-eclampsia" |
D. Unclassifiable antenatally | Hypertension with or without systemic manifestations if blood pressure was first recorded after 20 weeks' gestation. Reassessment is necessary at or after 42 d post partum. If the hypertension has resolved by then, the condition should be reclassified as gestational hypertension with or without proteinuria; if the hypertension has not resolved by then, the condition should be reclassified as pre-existing hypertension |