Evidence-based medicine and chelation therapy Here's what the Institute for Clinical Evaluative Sciences in Ontario (ICES) says about chelation therapy: "This therapy involves intravenous or intramuscular administration of ethylenediamine tetra-acetate (EDTA), usually accompanied by vitamins and minerals, and is intended to reduce coronary artery plaques. The currently available research does not provide acceptable evidence that there is any benefit from EDTA chelation therapy. However, there has been little in the way of adequate published trials using current standards of evidence to support or refute this therapy. At least one prospective trial under way may provide better evidence." [Return to text] | CMAJ September 15, 1997 (vol 157, no 6) / JAMC le 15 septembre 1997 (vol 157, no 6) |