Table 1: Meta-analyses of randomized controlled trials (RCTs) of lifestyle modifications (hospital admission, strict bed rest, care in hospital day-care unit, outpatient care or aerobic exercise) in the management or prevention of gestational hypertension | ||||
Interventions | Outcomes measured | Total sample size | No. of RCTs | OR (and 95% CI)* |
Admission to hospital v. home care for women with nonproteinuric hypertension26 | Diastolic pressure > 109 mm Hg | 353 | 2 | 0.74 (0.45-1.21) |
Proteinuria | 353 | 2 | 0.70 (0.38-1.26) | |
Eclampsia | 408 | 3 | 6.70 (0.13-...) | |
Admission to hospital with strict bed rest or with ambulation for women with proteinuric hypertension27 | Diastolic pressure > 109 mm Hg | 105 | 1 | 1.83 (0.72-4.33) |
Increased severity of proteinuria | 105 | 1 | 0.49 (0.20-1.17) | |
Fulminating pre-eclampsia | 145 | 2 | 1.96 (0.97-3.94) | |
Eclampsia | 145 | 2 | 0.13 (0.001-6.69) | |
Care in physician's office v. care in hospital day-care unit for women with nonproteinuric hypertension13 | Admission to hospital | 54 | 1 | 8.80 (3.00-25.80) |
Proteinuria | 54 | 1 | 11.40 (1.80-71.40) | |
Induction of labour | 54 | 1 | 4.90 (1.60-13.80) | |
Aerobic exercise v. no exercise28 | Pre-eclampsia | 82 | 2 | 1.21 (0.36-4.07) |
*OR = odds ratio, CI = confidence interval.
Infinity denoted as ... Statistically significant. |