Table 2: Selected drugs metabolized by cytochrome P-450 isoenzymes 1A2, 2C, 2D6 and 3A429,30
1A2	2C	2D6		3A4
Antidepressants Amitriptyline Clomipramine Fluvoxamine Imipramine Antipsychotics Clozapine Haloperidol Beta-blockers Propranolol Calcium-channel blockers Verapamil Miscellaneous Acetaminophen Caffeine Phenacetin Tacrine Theophylline	Antidepressants Amitriptyline Citalopram Clomipramine Imipramine Moclobemide Barbiturates Hexobarbital Mephobarbital Benzodiazepines Diazepam Beta-blockers Propranolol Miscellaneous Omeprazole Phenytoin Proguanil Tolbutamide Warfarin	Antiarrhythmics Encainide Flecainide Mexiletine Propafenone Antidepressants Amitriptyline Clomipramine Desipramine Fluoxetine Imipramine Maprotiline Nortriptyline N-desmethylcitalopram  Paroxetine Trazodone Trimipramine Venlafaxine	Antipsychotics Clozapine Haloperidol Perphenazine Risperidone Thioridazine Zuclopenthixol Beta-blockers Metoprolol Propranolol Timolol Opiates Codeine Dextromethorphan Ethylmorphine Miscellaneous 4-hydroxy-amphetamine Phenformin	Antiarrhythmics Lidocaine Propafenone Quinidine Antidepressants Amitriptyline Clomipramine Imipramine Nefazodone Sertraline Antihistamines Astemizole Terfenadine Benzodiazepines Alprazolam Midazolam Triazolam	Calcium-channel blockers Diltiazem Felodipine Nifedipine Verapamil Opiates Dextromethorphan Miscellaneous Carbamazepine Cortisol Cyclosporine Dexamethasone Erythromycin Ethinyl estradiol Tamoxifen Vinblastine

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