Increase in Alzheimer's disease: Artifact or real?
CMAJ 1998;158:1271
In response to: P. Rutter
Dr. Rutter's impression, based on his clinical experience, of an increasing incidence of dementia above and beyond that which could be accounted for by the aging of our population may be validated by ongoing incidence studies involving large randomized samples, such as the Canadian Study of Health and Aging.
Although predisposing genetic factors have attracted a great deal of interest in recent years, acquired factors in both our inner and outer environments are very important in the age at onset of Alzheimer's disease. Knowledge of these acquired, potentially modifiable factors could lead to effective prevention strategies.
Serge Gauthier, MD
Professor
Departments of Neurology, Psychiatry
and Medicine
McGill University
Director
Alzheimer's Disease Research Unit
McGill Centre for Studies in Aging
Montreal, Que.
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