Table 1: Options for treating erectile dysfunction after radical prostatectomy |
Option |
Benefit |
Problems |
Do nothing |
Little "fuss" |
May go against patient’s, partner’s and society’s expectations |
Intracavernous injection of prostaglandin |
Prompt, reliable erection
Probably most effective |
Intrusive |
Transurethral suppository (prostaglandin) |
Prompt and safe
40% efficacy |
Mildly intrusive |
Older oral agents |
Non-intrusive |
Seldom effective |
New oral agent (sildenafil) |
Non-intrusive
Efficacy probably similar to injection |
Contraindicated if patient is receiving nitrates*
1-h onset time |
Other new agents (e.g., phentolamine or apomorphine) |
Non-intrusive
Variable efficacy |
Depends on drug class |
Vacuum erection device |
Effective |
Intrusive, results in cold penis |
Penile prosthesis |
Effective |
Invasive, irreversible |
*It is unusual for patients who have undergone prostatectomy to use nitrates. |