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CMAJ
CMAJ - August 8, 2000JAMC - le 8 aout 2000

Bioflavonoids linked to childhood leukemia

CMAJ 2000;163(3):324

In a search for environmental causes of infant leukemia Reiner Strick and colleagues have shown in both in vivo and in vitro experiments that bioflavonoids, commonly found in some fruits and vegetables, may induce chromosomal translocation of the MLL gene in utero (Proc Natl Acad Sci USA 2000;97:4790-5). MLL gene translocations occur in about 80% of infants with leukemia.

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