HIV-1 Strain and Primary Drug Resistance in Canada

Surveillance Report to June 30, 2001

PDF Version (435 KB)

December 2001

Division of HIV/AIDS Epidemiology and Surveillance
National HIV and Retrovirology Laboratories
Centre for Infectious Disease Prevention and Control
Public Health Agency of Canada
Health Canada

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Table of Contents

• Information to the readers of HIV-1 Strain and Primary Drug Resistance in Canada
• Canadian HIV Strain and Drug Resistance Program
  Contact Information – Health Canada
• Canadian HIV Strain and Drug Resistance Surveillance Program
  Contact Information – Provincial Partners
• Results at a Glance
• An Overview of the Canadian HIV Strain and Drug Resistance Surveillance Program 
  • Figure 1. Date collection, transfer and analysis
    • Goals of the Canadian HIV Strain and Drug Resistance Surveillance Program
    • Methodology
  • Figure 2. Genetic testing algorithm used by the National Laboratory for HIV Genetics
• HIV-1 Primary Drug Resistance in Canada
  • Table 1. Prevalence of primary drug resistance among newly diagnosed, treatment naïve individuals
  • Table 2. Primary mutations in reverse transcriptase and in protease
  • Table 3. Epidemiologic characteristics of individuals infected with HIV-1 harbouring primary mutations (N=481)
  • Table 4. Summary of key studies on HIV-1 primary drug resistance in Canada
  • Table 5. Summary of key studies on HIV-1 primary drug resistance in the United States and in Western Europe
• HIV-1 SUBTYPES IN CANADA
  • Table 6. Distribution of HIV-1 subtypes in Canada
  • Table 7.  Prevalence of HIV-1 subtypes by provinces participating in the Canadian HIV Strain and Drug Resistance Surveillance Program
  • Table 8. Epidemiologic characteristics of individuals infected with HIV-1 subtype B versus non-B subtypes
• National HIV Reference Services
  • Table 9. HIV-1 subtype distribution of 26 samples submitted to the National HIV Laboratory  for Reference Services by province and year of first positive diagnosis
• Technical Notes
• Data Limitations
• Appendix 1. Glossary of terms
• Appendix 2. List of primary mutations

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