Table of Contents

• Acknowledgements
• Summary
• List of abbreviations
• Introduction
• Burden of Disease
• Vaccine Characteristics

• Immunization Strategies
• Cost-effectiveness
• Program Acceptability
• Program Feasibility
• Program Evaluation
• Research Questions
• Other Considerations
• CIC Recommendation for Use of Meningococcal Vaccines
• Recommended Immunization Program
• Conclusion
• References

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Acknowledgement

The Centre for Immunization and Respiratory Infections of the Public Health Agency of Canada, through a contract with Dr. Philippe De Wals from the Public Health Research Unit, Quebec University Hospital Research Centre, requested an evaluation of the quadrivalent meningococcal vaccine using the Erickson, De Wals and Farand Analytical Framework. This report is primarily based on the evaluation provided by Dr. De Wals and represents available epidemiological and economical information up to Sept.2007. The information on the burden of disease and the vaccine characteristics has been updated in a statement from the National Advisory Committee on Immunization (NACI) in 2009.

The scientific review, critical analysis and expert opinion presented by Dr. De Wals in this report are acknowledged.

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