Table 4: Studies of the effectiveness of surgical treatment of obesity |
Study |
No. of patients (no. of women) |
Length of follow-up |
Patients lost to follow-up |
Intervention
groups |
Mean baseline weight or BMI |
Mean weight loss/gain at follow-up, kg |
Comments |
Randomized controlled trials |
Andersen et al73 |
57 |
(50) |
5 yr |
1 |
A: VLCD
B: LCD + gastroplasty |
A: 115 kg
B: 120 kg |
A: -26.8
B: -18.2 |
A: 21/30 patients regained most weight loss (within 1 kg of baseline weight)
B: 16/27 patients regained most weight loss (within 1 kg of baseline weight) |
Hall et al74 |
310 |
(288) |
3 yr |
52 |
A: Gastric bypass
B: Gastro-
plasty
C: Gastro-
gastrostomy |
A: 110 kg
B: 112 kg
C: 115 kg |
A: -17
B: -31
C: -39 |
66% of patients in group A, 44% in group B and 16% in group C had > 50% excess weight loss |
Naslund et al75 |
57 |
(51) |
2 yr |
0 |
A: Gastric bypass
B: Gastro-
plasty |
A: 117.7 kg
B: 117.8 kg |
A: -42.9
B: -27.6 |
|
Lechner et al76 |
112 |
(NA) |
|
|
A: Gastric bypass
B: Gastro-
plasty |
A: 119.9 kg
B: 118.6 kg |
A: -45.5
B: -28.8 |
|
Prospective cohort study |
Ashley et al77 |
114 |
(96) |
648 mo |
5 |
Gastroplasty |
BMI 44.8 |
NA |
31 of 47 patients followed up for 2 yr regained > 50% of lost weight |