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CMAJ
CMAJ - April 20, 1999JAMC - le 20 avril 1999

Tuberculosis: 3. Epidemiology of the disease in Canada

Table 6: Risk factors for TB

Characteristics associated with higher risk of infection with tubercle bacilli

Country of origin with high prevalence of TB
Aboriginal background
Homelessness
Substance abuse
Time spend in a correctional facility
Contact with a person who has TB
Older age
Travel to a high-prevalence country
Health care occupation
Other occupational contact with a high-prevalence group (e.g., foreign-born people, aboriginal people)

Characteristics associated with higher risk of progression from tuberculous infection to disease
HIV seropositivity
Diabetes (especially poorly controlled insulin-dependent diabetes)
Alcohol abuse
Other immunosuppressive illnesses
Long-term corticosteroid use (at least 15 mg prednisone per day for longer than 2 weeks)
Gastrectomy
Intravenous drug abuse
Malnutrition
End-stage renal disease, particularly if dependent on dialysis
Silicosis
Radiotherapy
Pregnancy or immediate postpartum period
Recent tubesculin conversion
Old, healed but untreated TB

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