Biosafety Programs and Resources

The Public Health Agency of Canada’s Pathogen Regulation Directorate (PRD) is responsible for the administration and enforcement of the Human Pathogens and Toxins Act (External link) (HPTA) and the Human Pathogens Importation Regulations (External link) (HPIR). As part of its efforts to promote compliance and reduce the risk to public health and safety, PRD provides biosafety training and tools to those who work with human pathogens and toxins. Providing these programs helps standardize procedures and mitigate risks, contributing to a biosafety and biosecurity regime that strengthens safe handling of pathogens and toxins which, in turn, protects the general public.

Pathogen Safety Data Sheets

PRD has approximately 200 Pathogen Safety Data Sheets (PSDS) (formerly Material Safety Data Sheets) for infectious substances available. These technical documents provide detailed descriptions of the hazardous properties of specific human pathogens or toxins and recommendations for work practices involving these agents. The PSDS have been under revision and the updated material is posted as it becomes available.

Canadian Biosafety Standards and Guidelines

The Public Health Agency of Canada and the Canadian Food Inspection Agency are currently working together to create an updated set of Canadian Biosafety Standards and Guidelines (External link) (CBSG) in an effort to streamline biosafety requirements and lessen the impact on stakeholders regulated by both Agencies.

Biosafety Learning and Knowledge

PRD offers the following resources and services:

• Training Courses
• Biosafety Videos
  • Lab Biosafety 101
  • Containment Level 2 Laboratories
  • Containment Level 3 Laboratories
• Biosafety Film Loan Request
• A bibliography on biosafety issues.
• The Laboratory Biosafety Guidelines (LBG), a technical document developed for those who design, operate or work with human pathogens or toxins. Under the Human Pathogens Importation Regulations, compliance with the LBG is mandatory for those who import human pathogens or toxins into Canada. It is considered a best practice to comply with the LBG for non-importing facilities.
• Assistance to microbiological laboratories on the requirements outlined in the Laboratory Biosafety Guidelines. PRD is most frequently contacted regarding:
  • Planning laboratories from design to certification;
  • Problem-solving in regards to laboratory biosafety; and
  • Selection, installation and use of biological safety cabinets.

Biosafety Advisories and Special Biosafety Notifications

Biosafety Advisories are developed when the data obtained from a Risk Assessment of a new or emerging pathogen of interest indicates that new physical and/or operational requirements are required for persons to work with the pathogen safely. The new operational and/or physical requirements need to be disseminated to interested parties as soon as possible for the safe handling of the material; in order to ensure accuracy they are reviewed frequently as more information becomes available.

Special Biosafety Notifications are developed when the data obtained from a Risk Assessment for a particular pathogen indicates that no changes will be required to the pre-existing physical and operational requirements. The notification is created to emphasize these requirements to limit the spread of the particular pathogen.

For more information about the work of the Public Health Agency of Canada and the Pathogen Regulation Directorate, please call (613) 957-1779 or send an e-mail to biosafety.biosecurite@phac-aspc.gc.ca.

Pathogen Regulation Directorate
Public Health Agency of Canada
100 Colonnade Road, P.L.: 6201A
Ottawa, Ontario K1A 0K9